Ran Mano, Founder and Lead Strategist of Nuance Agency

Founder & Lead Strategist

Three decades building online

Ran Mano built his first website in 1994 and has worked in digital professionally since 1995. In the years since, he has led digital strategy for a Federal Reserve Bank, a Fortune 50 healthcare company, small agencies, and non-profits — and helped build an early web startup that was acquired by Ask Jeeves.

Est. online since 1994 St. Louis, Missouri MBA
30+
Years in digital
1994
First website built
500%
Audience growth at Centene
450%
SEO traffic lift at the Fed

Who I am

A builder before it was a category

"I built my first website in 1994, when 'web developer' wasn't yet a job title. I've been solving the same problem ever since: connecting a real business goal to the right digital experience."

Ran has spent his career at the intersection of strategy, design, and technology. He has hand-coded HTML, run enterprise centers of excellence, rebuilt corporate websites read by tens of millions, and set the social and SEO strategy for institutions where accuracy and reputation are non-negotiable.

That range is the point. He has sat on every side of the work — the scrappy startup, the boutique creative shop, the non-profit with more mission than budget, and the Fortune 50 enterprise — across healthcare, financial services, technology, and the creative sector. Nuance Agency is where that experience comes together for clients who want a senior partner, not a hand-off to junior staff.

The long view

A career measured in decades, not projects

2025 — Present

Nuance Agency

Founder & Lead Strategist

Founded a St. Louis creative and digital agency built on senior-level strategy: web, brand, creative, video, SEO & GEO, social, and AI enablement — every engagement grounded in strategy and measured against outcomes.

Agency
2015 — 2024

Centene Corporation

Vice President → Staff Vice President, Digital Communications

Led a team of digital professionals driving multichannel content strategy for a Fortune 50 healthcare enterprise. Grew social audience 500% and organic engagement 600%, built an Enterprise Center of Excellence for social and video adopted by 30 subsidiaries, cut video production costs 43% through centralization, and oversaw an intranet redesign serving 75,000 employees and 28 million annual page views.

Fortune 50 · Healthcare
2009 — 2015

Federal Reserve Bank of St. Louis

Senior Manager → Digital Communications Strategist

Launched the Bank's social media presence after the financial crisis and led the overhaul of stlouisfed.org. A focused SEO strategy grew site-wide traffic more than 240%, with targeted-page traffic up 450%. Coverage and citations followed from the Wall Street Journal, New York Times, Financial Times, The Economist, Bloomberg, and Forbes.

Financial Services
2006 — 2009

Mano Interactive

Founder & Managing Partner

Ran his own digital agency serving small and mid-sized firms — taking 28 websites from concept to launch, introducing e-commerce to organizations new to it, and managing up to nine concurrent projects across web, email, video, and search.

Agency
2004 — 2006

Jewish Federation of St. Louis

Web Manager

Conceived and built a community portal that connected more than 100 organizations, established content streams and a weekly e-newsletter, and grew traffic and returning visitors for a mission-driven non-profit.

Non-profit
2001 — 2004

Schwartz & Associates Creative

New Media Director / Video Editor

Produced content-driven websites for institutional and corporate clients including the Pulitzer Foundation for the Arts at Grand Center, and edited nationally distributed video — the boutique-creative chapter that shaped his design and storytelling sensibility.

Creative
1999 — 2001

Ask Jeeves (ask.com)

New Media Director

After the educational startup he helped build was acquired by Ask Jeeves, Ran led a group of 11 developers and writers on the flagship educational domain and served as technical liaison between the St. Louis office and corporate headquarters.

Technology · Search
1995 — 1999

The Evergreen Project

New Media Designer · Early-stage startup

Sole interactive developer at a small educational-technology startup, later acquired by Ask Jeeves. Produced 15 CD-ROM titles and built an educational website for the Missouri Botanical Garden that won an international award from Cable & Wireless.

Startup · Acquired
1994

The first website

Where it started

Built his first website by hand — the beginning of a career that has tracked the entire modern history of the web, from static HTML to AI answer engines.

Origin

Selected results

Numbers that held up

500%

Audience growth

Increase in social media audience at Centene after building and executing a multichannel content strategy.

450%

Targeted SEO traffic

Growth in traffic to targeted pages at the Federal Reserve Bank of St. Louis through a focused content and SEO program.

600%

Organic engagement

Lift in organic engagement across Centene's digital channels under his content strategy.

43%

Lower video costs

Reduction in production costs after centralizing enterprise video, with more consistent messaging and design.

28M

Annual page views

On the redesigned intranet serving 75,000 employees across a Fortune 50 enterprise.

240%

Site-wide traffic

Overall traffic growth at stlouisfed.org from search optimization, social, and automated email alerts.

Recognition & leadership

Trusted by peers and press

  • Business Insider — named to "The 102 People to Follow on Twitter" for three consecutive years.
  • SocialMedia.org — Board Chair (2018–2024) of the vendor-free membership organization for people leading social media at major companies.
  • Cable & Wireless — international award for an educational website built for the Missouri Botanical Garden.
  • National press citations — work featured or cited by the Wall Street Journal, New York Times, Financial Times, The Economist, Bloomberg, and Forbes.

Education

Strategy meets the technical

  • Saint Louis University — Master of Business Administration (MBA).
  • Washington University in St. Louis — Bachelor of Arts, Economics & History.
  • WashU Olin Business School — Executive Program, Leadership for High Performance.

Areas of expertise

Digital Strategy SEO & GEO Content Strategy Brand Reputation Web Development Social Media Video Production UX & Accessibility AI Enablement Analytics

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